Vabrasio is a reliable test to rule out endometrial cancer.
نویسندگان
چکیده
INTRODUCTION Endometrial cancer is the most common gynaecological cancer in Denmark, and its incidence peaks in the postmenopausal years. The aim of the present study was to evaluate the effectiveness of vacuum aspirator (vabrasio) for the detection of endometrial cancer in terms of sensitivity, specificity and predictive value. METHODS A cohort counting 503 women who had vabrasio was evaluated retrospectively. The women included were consecutive patients who had received vabrasio at the Department of Gynaecology and Obstetrics at Herning Hospital, Denmark, during a two-year period. They were identified by searching the hospital database for the International Classification of Diseases, tenth version (ICD-10) code for vabrasio. RESULTS The indications for vabrasio were postmenopausal bleeding (45%), meno/metrorrhagia (43%) and thickened endometrium/polyp (6%). The first evaluation by vabrasio was normal in 381 women (76%), insufficient in 83 women (17%), 22 (4%) had endometrial cancer and 17 (3%) had another non-malignant diagnosis. The first evaluation for cancer with vabrasio had a sensitivity of 81%, a specificity of 100% and predictive values of 100% (positive) and 99% (negative). CONCLUSION Vabrasio has a good diagnostic reliability with respect to endometrial cancer, but has some shortcomings due to insufficient sampling for diagnosis. FUNDING none. TRIAL REGISTRATION not relevant. Danish Data Protection Agency: case no.: 1-16-02-601-14.
منابع مشابه
EVALUATION OF DIAGNOSTIC ACCURACY OF PREHYSTERECTOMY CURETTAGE IN DETERMINING TUMOR TYPE IN THE PATIENTS WITH ENDOMETRIAL CANCER IN SHAHID MOTAHARI HOSPITAL IN URMIA, IRAN
Background & Aims: The use of curettage in the diagnosis of endometrial disorders is very widespread, and is the most common diagnostic method before performing hysterectomy. Various studies have been performed to compare the pathological results obtained from curettage with the final pathological results of hysterectomy. The results of some of these studies indicated high efficiency of curetta...
متن کاملNapsin-A Expression, a Reliable Immunohistochemical Marker for Diagnosis of Ovarian and Endometrial Clear Cell Carcinomas
Background & Objective: Clear cell carcinomas (CCC) differ from other types of ovarian and endometrial carcinomas in biolo...
متن کاملSignificance of laboratory studies for ruling out metastases in primary endometrial carcinoma.
BACKGROUND At the time of initial diagnosis of endometrial cancer, therapeutic decisions depend on the recognition of remote metastases. Tumor markers and hepatic enzymes are frequently used to screen for metastases. This study aimed to assess the clinical value of serum concentrations of tumor markers and liver enzymes. PATIENTS AND METHODS Laboratory test results from all patients with the ...
متن کاملThe use of new and old ultrasound techniques in the assessment of women with postmenopausal bleeding
Introduction Postmenopausal bleeding (PMB) is the most common symptom of the endometrium. Cervical cancer must also not be forgotten, especially in women with a thin endometrium. Therefore, all women presenting with PMB should undergo evaluation with transvaginal ultrasound to estimate the risk of endometrial cancer, and speculum examination/cervical cytology to rule out cervical pathology. Man...
متن کاملAssociation Rule- Spatial Data Mining Approach for Exploration of Endometrial Cancer Data
Cancer is increasing the total number of unexpected deaths around the world. Until now, cancer research could not significantly contribute to a proper solution for the cancer patient, and as a result, the high death rate is uncontrolled. The present research aim is to extract the significant factors for responsible for endometrial cancer. We subsequently employed association rule mining algorit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Danish medical journal
دوره 62 8 شماره
صفحات -
تاریخ انتشار 2015